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Viruses are the most common cause of respiratory tract infections (RTIs), yet in contrast to the plethora of antibiotics available for the treatment of bacterial RTI, until very recently only three agents were widely approved for the treatment of viral RTIs: amantadine and rimantadine for influenza A, and ribavirin for respiratory syncytial virus (RSV) infection—and amantadine was first marketed in 1966.
In 1999 the novel anti-influenza agents, zanamivir and oseltamivir, were launched.
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particularly COPD, asthma, cardiac disease and diabetes.
Viral pneumonias are uncommon in the previously healthy and are most commonly associated with influenza, but also occur rarely owing to measles and varicella-zoster infection.
Some 20% of colds are caused by coronavirus infection; identical symptoms can be caused by influenza and parainfluenza viruses, adenoviruses, RSV and various enteroviruses.
The same viruses cause descending infections of the respiratory tract, but the aetiology differs in frequency; adenoviruses are common causes of viral pharyngitis and tonsillitis, while croup (subglottic oedema due to laryngotracheitis) is particularly associated with parainfluenza virus infection.